South African bowler Dale Steyn (R) celebrates the dismissal of Australian Batsman Steven Smith (L) during the second One Day International (ODI) cricket match Australia versus South Africa at the Wanderers Stadium in Johannesburg on October 2, 2016. GIANLUIGI GUERCIA/AFP/Getty Images

Australia have slumped to a 142-run defeat in the second one-day international against South Africa, completing a miserable sporting weekend for Australian teams in Johannesburg.

The Proteas hold a 2-0 lead in the five-match series after backing up their six- wicket win on Friday at Centurion with an even more dominant display at the Wanderers on Sunday.

Proteas captain Faf du Plessis top-scored with 111 as Australia’s understrength bowling line-up was again put to the sword.

Combining with JP Duminy (82) in a 150-run third-wicket stand, South Africa surged to an imposing 6-361 off their 50 overs.

In reply, David Warner (50) and Travis Head (51) both made half-centuries, but Australia were never realistically in the hunt for the target as they were dismissed for 219 with 12 overs to spare.