Kane Richardson will be forced out of Australia's white ball tour to Pakistan, with the man who was set to lead the attack succumbing to a hamstring injury.
Cricket Australia have confirmed he will be replaced for the series by New South Wales and Sydney Sixers bowler, Ben Dwarshuis.
Tight security and coronavirus bubble arrangements mean a large chunk of the Test squad will head home at the conclusion of the third and final five-day event in Lahore this week.
They include the leading quicks Mitchell Starc, Josh Hazlewood and Pat Cummins, leaving an inexperienced attack to take over with three ODIs and a single T20 ahead before Australia exits Pakistan and prepares for their next challenge - a winter tour of Sri Lanka with dates still to be announced.
The Aussie's ODI squad already had an exceedingly inexperienced attack for the series, but Richardson pulling out and being replaced by Dwarshuis will mean it is one of the most inexperienced attacks Australia has ever fielded in any format of the game.
Dwarshuis, who is set to potentially make his ODI debut on the tour, will be joined by Jason Behrendorff, Sean Abbott and Nathan Ellis. Ellis and Dwarshuis are both yet to debut in the 50-over format, while Abbott only has two matches to his name. Behrendorff has played 11. Dwarshuis is the only one of the four yet to make his T20I debut.
Dwarshuis put together an excellent Big Bash campaign for the Sixers, who eventually made the final, and has been solid for the Blues in domestic cricket.
Captain Aaron Finch said the team was ready.
"One thing that will help is the guys have played a lot of T20 cricket," Finch said.
"They're quite inexperienced for Australia but I think playing T20 cricket will help them in that regard. There's a lot of skill in the group and guys that have been around one-day cricket for a long time domestically as well.
"Having a lot of a lot of faith in their own ability is really important.
"When you have got guys like Abbott, he's been around (international cricket) for a long time, Behrendorff (as well) – they've played a lot of state cricket, so I think it'll be fine."
Australia ODI and T20 squad
Aaron Finch (c), Sean Abbott, Ashton Agar, Jason Behrendorff, Alex Carey, Ben Dwarshuis, Nathan Ellis, Cameron Green, Travis Head, Josh Inglis, Marnus Labuschagne, Mitchell Marsh, Ben McDermott, Steve Smith, Marcus Stoinis, Adam Zampa
Series fixtures
March 29: First ODI, Lahore
March 31: Second ODI, Lahore
April 2: Third ODI, Lahore
April 5: Only T20I, Lahore
